Favà A, Donadeu L, Sabé N, Pernin V, González-Costello J, Lladó L, Meneghini M, Charmetant X, García-Romero E, Cachero A, Torija A, Rodriguez-Urquia R, Crespo E, Teubel I, Melilli E, Montero N, Manonelles A, Preyer R, Strecker K, Ovize A, Lozano JJ, Sidorova J, Cruzado JM, Le Quintrec M, Thaunat O, Bestard O. SARS-CoV-2-specific serological and functional T cell immune responses during acute and early COVID-19 convalescence in solid organ transplant patients. Am J Transplant. 2021 Mar 23

Carrasco R, Izquierdo L, van der Heijden AG, Lozano JJ, Franco M, Ingelmo- Torres M, Roldan FL, Llorens M, Ribal MJ, Mengual L, Alcaraz A. Differential gene expression profile between progressive and de novo muscle invasive bladder cancer and its prognostic implication. Sci Rep. 2021 Mar 17;11(1):6132

Blaya D, Pose E, Coll M, Lozano JJ, Graupera I, Schierwagen R, Jansen C, Castro P, Fernandez S, Sidorova J, Vasa-Nicotera M, Solà E, Caballería J, Trebicka J, Ginès P, Sancho-Bru P. Profiling circulating microRNAs in patients with cirrhosis and acute-on-chronic liver failure. JHEP Rep. 2021 Jan 19;3(2):100233

Weiss E, de la Grange P, Defaye M, Lozano JJ, Aguilar F, Hegde P, Jolly A, Moga L, Sukriti S, Agarwal B, Gurm H, Tanguy M, Poisson J, Clària J, Abback PS, Périanin A, Mehta G, Jalan R, Francoz C, Rautou PE, Lotersztajn S, Arroyo V, Durand F, Moreau R. Characterization of Blood Immune Cells in Patients With Decompensated Cirrhosis Including ACLF. Front Immunol. 2021 Feb 5;11:619039

Guldiken N, Argemi J, Gurbuz B, Atkinson SR, Oliverius M, Fila P, Hamesch K, Bruns T, Cabezas J, Lozano JJ, Mann J, Cao S, Mathurin P, Shah VH, Trautwein C, Thursz MR, Bataller R, Strnad P. Serum transferrin as a biomarker of hepatocyte nuclear factor 4 alpha activity and hepatocyte function in liver diseases. BMC Med. 2021 Feb 17;19(1):39

Canals D, Salamone S, Santacreu BJ, Aguilar D, Hernandez-Corbacho MJ, Ostermeyer-Fay AG, Greene M, Nemeth E, Haley JD, Obeid LM, Hannun YA. The doxorubicin-induced cell motility network is under the control of the ceramide- activated protein phosphatase 1 alpha. FASEB J. 2021 Mar;35(3):e21396

Revilla L, Mayorgas A, Corraliza AM, Masamunt MC, Metwaly A, Haller D, Tristán E, Carrasco A, Esteve M, Panés J, Ricart E, Lozano JJ, Salas A. Multi- omic modelling of inflammatory bowel disease with regularized canonical correlation analysis. PLoS One. 2021 Feb 8;16(2):e0246367

Herrera-Pariente C, Capó-García R, Díaz-Gay M, Carballal S, Muñoz J, Llach J, Sánchez A, Bonjoch L, Arnau-Collell C, Soares de Lima Y, Golubicki M, Jung G, Lozano JJ, Castells A, Balaguer F, Bujanda L, Castellví-Bel S, Moreira L. Identification of New Genes Involved in Germline Predisposition to Early-Onset Gastric Cancer. Int J Mol Sci. 2021 Jan 28;22(3):1310

Merid SK, Bustamante M, Standl M, Sunyer J, Heinrich J, Lemonnier N, Aguilar D, Antó JM, Bousquet J, Santa-Marina L, Lertxundi A, Bergström A, Kull I, Wheelock ÅM, Koppelman GH, Melén E, Gruzieva O. Integration of gene expression and DNA methylation identifies epigenetically controlled modules related to PM_2.5 exposure. Environ Int. 2021 Jan;146:106248

2020

García-López M, Lens S, Pallett LJ, Testoni B, Rodríguez-Tajes S, Mariño Z, Bartres C, García-Pras E, Leonel T, Perpiñán E, Lozano JJ, Rodríguez-Frías F, Koutsoudakis G, Zoulim F, Maini MK, Forns X, Pérez-Del-Pulgar S. Viral and immune factors associated with successful treatment withdrawal in HBeAg-negative chronic hepatitis B patients. J Hepatol. 2020 Dec 2:S0168-8278(20)33830-7

Zaccherini G, Aguilar F, Caraceni P, Clària J, Lozano JJ, Fenaille F, Castelli F, Junot C, Curto A, Formentin C, Weiss E, Bernardi M, Jalan R, Angeli P, Moreau R, Arroyo V. Assessing the role of amino acids in systemic inflammation and organ failure in patients with ACLF. J Hepatol. 2020 Dec 1:S0168-8278(20)33821-6

Mercado-Gómez M, Lopitz-Otsoa F, Azkargorta M, Serrano-Maciá M, Lachiondo- Ortega S, Goikoetxea-Usandizaga N, Rodríguez-Agudo R, Fernández-Ramos D, Bizkarguenaga M, Juan VG, Lectez B, Aloria K, Arizmendi JM, Simon J, Alonso C, Lozano JJ, Avila MA, Banales JM, Marin JJG, Beraza N, Mato JM, Elortza F, Barrio R, Sutherland JD, Mayor U, Martínez-Chantar ML, Delgado TC. Multi-Omics Integration Highlights the Role of Ubiquitination in CCl4-Induced Liver Fibrosis. Int J Mol Sci. 2020 Nov 27;21(23):9043

Jiménez N, Reig Ò, Montalbo R, Milà-Guasch M, Nadal-Dieste L, Castellano G, Lozano JJ, Victoria I, Font A, Rodriguez-Vida A, Carles J, Suárez C, Domènech M, Sala-González N, Fernández PL, Rodríguez-Carunchio L, Díaz S, Prat A, Marín- Aguilera M, Mellado B. Cell Plasticity-Related Phenotypes and Taxanes Resistance in Castration-Resistant Prostate Cancer. Front Oncol. 2020 Nov 2;10:594023

Pose E, Coll M, Martínez-Sánchez C, Zeng Z, Surewaard BGJ, Català C, Velasco M, Lozano J, Ariño S, Fuster D, Niñerola-Bazán A, Graupera I, Muñoz É, Lozano F, Sancho-Bru P, Kubes P, Ginès P. PD-L1 is overexpressed in liver macrophages in chronic liver diseases and its blockade improves the antibacterial activity against infections. Hepatology. 2020 Nov 20

Carrion A, Ingelmo-Torres M, Lozano JJ, Montalbo R, D'Anna M, Mercader C, Velez E, Ribal MJ, Alcaraz A, Mengual L. Prognostic classifier for predicting biochemical recurrence in localized prostate cancer patients after radical prostatectomy. Urol Oncol. 2020 Nov 11:S1078-1439(20)30565-2

Flores-Costa R, Duran-Güell M, Casulleras M, López-Vicario C, Alcaraz-Quiles J, Diaz A, Lozano JJ, Titos E, Hall K, Sarno R, Masferrer JL, Clària J. Stimulation of soluble guanylate cyclase exerts antiinflammatory actions in the liver through a VASP/NF-κB/NLRP3 inflammasome circuit. Proc Natl Acad Sci U S A. 2020 Nov 10;117(45):28263-28274

Pietrosi G, Fernández-Iglesias A, Pampalone M, Ortega-Ribera M, Lozano JJ, García-Calderó H, Abad-Jordà L, Conaldi PG, Parolini O, Vizzini G, Luca A, Bosch J, Gracia-Sancho J. Human amniotic stem cells improve hepatic microvascular dysfunction and portal hypertension in cirrhotic rats. Liver Int. 2020 Oct;40(10):2500-2514

Lario S, Ramírez-Lázaro MJ, González-Lahera A, Lavín JL, Vila-Casadesús M, Quílez ME, Brunet-Vega A, Lozano JJ, Aransay AM, Calvet X. Cross-sectional study of human coding- and non-coding RNAs in progressive stages of Helicobacter pylori infection. Sci Data. 2020 Sep 8;7(1):296

Prieto-Fernández E, Lopez-Lopez E, Martin-Guerrero I, Bárcena L, Gonzalez- Lopez M, Aransay AM, Lozano JJ, Benito J, Falcón-Pérez JM, Garcia-Orad A. Variability in Cerebrospinal Fluid MicroRNAs Through Life. Mol Neurobiol. 2020 Oct;57(10):4134-4142

Figueiredo AM, Villacampa P, Diéguez-Hurtado R, José Lozano J, Kobialka P, Cortazar AR, Martinez-Romero A, Angulo-Urarte A, Franco CA, Claret M, Aransay AM, Adams RH, Carracedo A, Graupera M. Phosphoinositide 3-Kinase-Regulated Pericyte Maturation Governs Vascular Remodeling. Circulation. 2020 Aug 18;142(7):688-704

Canals D, Salamone S, Santacreu BJ, Nemeth E, Aguilar D, Hernandez-Corbacho MJ, Adada M, Staquicini DI, Arap W, Pasqualini R, Haley J, Obeid LM, Hannun YA. Ceramide launches an acute anti-adhesion pro-migration cell signaling program in response to chemotherapy. FASEB J. 2020 Jun;34(6):7610-7630

Vila-Navarro E, Fernandez-Castañer E, Rovira-Rigau M, Raimondi G, Vila- Casadesus M, Lozano JJ, Soubeyran P, Iovanna J, Castells A, Fillat C, Gironella M. MiR-93 is related to poor prognosis in pancreatic cancer and promotes tumor progression by targeting microtubule dynamics. Oncogenesis. 2020 May 4;9(5):43

Palomo-Irigoyen M, Pérez-Andrés E, Iruarrizaga-Lejarreta M, Barreira- Manrique A, Tamayo-Caro M, Vila-Vecilla L, Moreno-Cugnon L, Beitia N, Medrano D, Fernández-Ramos D, Lozano JJ, Okawa S, Lavín JL, Martín-Martín N, Sutherland JD, de Juan VG, Gonzalez-Lopez M, Macías-Cámara N, Mosén-Ansorena D, Laraba L, Hanemann CO, Ercolano E, Parkinson DB, Schultz CW, Araúzo-Bravo MJ, Ascensión AM, Gerovska D, Iribar H, Izeta A, Pytel P, Krastel P, Provenzani A, Seneci P, Carrasco RD, Del Sol A, Martinez-Chantar ML, Barrio R, Serra E, Lazaro C, Flanagan AM, Gorospe M, Ratner N, Aransay AM, Carracedo A, Varela-Rey M, Woodhoo A. HuR/ELAVL1 drives malignant peripheral nerve sheath tumor growth and metastasis. J Clin Invest. 2020 Jul 1;130(7):3848-3864

Lim SP, Costantini B, Mian SA, Perez Abellan P, Gandhi S, Martinez Llordella M, Lozano JJ, Antunes Dos Reis R, Povoleri GAM, Mourikis TP, Abarrategi A, Ariza-McNaughton L, Heck S, Irish JM, Lombardi G, Marsh JCW, Bonnet D, Kordasti S, Mufti GJ. Treg sensitivity to FasL and relative IL-2 deprivation drive idiopathic aplastic anemia immune dysfunction. Blood. 2020 Aug 13;136(7):885-897

Lemonnier N, Melén E, Jiang Y, Joly S, Ménard C, Aguilar D, Acosta-Perez E, Bergström A, Boutaoui N, Bustamante M, Canino G, Forno E, Ramon González J, Garcia-Aymerich J, Gruzieva O, Guerra S, Heinrich J, Kull I, Ibarluzea Maurolagoitia J, Santa-Marina Rodriguez L, Thiering E, Wickman M, Akdis C, Akdis M, Chen W, Keil T, Koppelman GH, Siroux V, Xu CJ, Hainaut P, Standl M, Sunyer J, Celedón JC, Maria Antó J, Bousquet J. A novel whole blood gene expression signature for asthma, dermatitis, and rhinitis multimorbidity in children and adolescents. Allergy. 2020 Apr 11

Moreau R, Clària J, Aguilar F, Fenaille F, Lozano JJ, Junot C, Colsch B, Caraceni P, Trebicka J, Pavesi M, Alessandria C, Nevens F, Saliba F, Welzel TM, Albillos A, Gustot T, Fernández J, Moreno C, Baldassarre M, Zaccherini G, Piano S, Montagnese S, Vargas V, Genescà J, Solà E, Bernal W, Butin N, Hautbergue T, Cholet S, Castelli F, Jansen C, Steib C, Campion D, Mookerjee R, Rodríguez- Gandía M, Soriano G, Durand F, Benten D, Bañares R, Stauber RE, Gronbaek H, Coenraad MJ, Ginès P, Gerbes A, Jalan R, Bernardi M, Arroyo V, Angeli P; CANONIC Study Investigators of the EASL Clif Consortium; Grifols Chair and the European Foundation for the Study of Chronic Liver Failure (EF Clif). Correction to 'Blood metabolomics uncovers inflammation-associated mitochondrial dysfunction as a potential mechanism underlying ACLF' [J Hepatol 2020 (72) 688-701]. J Hepatol. 2020 Jun;72(6):1218-1220

Arnau-Collell C, Soares de Lima Y, Díaz-Gay M, Muñoz J, Carballal S, Bonjoch L, Moreira L, Lozano JJ, Ocaña T, Cuatrecasas M, Díaz de Bustamante A, Castells A, Capellà G, Bujanda L, Cubiella J, Rodríguez-Alcalde D, Balaguer F, Ruiz-Ponte C, Valle L, Moreno V, Castellvi-Bel S. Colorectal cancer genetic variants are also associated with serrated polyposis syndrome susceptibility. J Med Genet. 2020 Oct;57(10):677-682

da Silva FAR, Pascoal LB, Dotti I, Setsuko Ayrizono ML, Aguilar D, Rodrigues BL, Arroyes M, Ferrer-Picon E, Milanski M, Velloso LA, Fagundes JJ, Salas A, Leal RF. Whole transcriptional analysis identifies markers of B, T and plasma cell signaling pathways in the mesenteric adipose tissue associated with Crohn's disease. J Transl Med. 2020 Jan 30;18(1):44

Franch-Expósito S, Bassaganyas L, Vila-Casadesús M, Hernández-Illán E, Esteban-Fabró R, Díaz-Gay M, Lozano JJ, Castells A, Llovet JM, Castellví-Bel S, Camps J. CNApp, a tool for the quantification of copy number alterations and integrative analysis revealing clinical implications. Elife. 2020 Jan 15;9:e50267

Duran-Sanchon S, Vila-Navarro E, Marcuello M, Lozano JJ, Muñoz J, Cubiella J, Diez MS, Bujanda L, Lanas A, Jover R, Hernández V, Quintero E, Herreros- Villanueva M, Martín AC, Pérez-Palacios R, Arroyo R, Castells A, Gironella M. Validation of miR-1228-3p as Housekeeping for MicroRNA Analysis in Liquid Biopsies from Colorectal Cancer Patients. Biomolecules. 2019 Dec 20;10(1):16

Moreau R, Clària J, Aguilar F, Fenaille F, Lozano JJ, Junot C, Colsch B, Caraceni P, Trebicka J, Pavesi M, Alessandria C, Nevens F, Saliba F, Welzel TM, Albillos A, Gustot T, Fernández J, Moreno C, Baldassarre M, Zaccherini G, Piano S, Montagnese S, Vargas V, Genescà J, Solà E, Bernal W, Butin N, Hautbergue T, Cholet S, Castelli F, Jansen C, Steib C, Campion D, Mookerjee R, Rodríguez- Gandía M, Soriano G, Durand F, Benten D, Bañares R, Stauber RE, Gronbaek H, Coenraad MJ, Ginès P, Gerbes A, Jalan R, Bernardi M, Arroyo V, Angeli P; CANONIC Study Investigators of the EASL Clif Consortium; Grifols Chair; European Foundation for the Study of Chronic Liver Failure (EF Clif). Blood metabolomics uncovers inflammation-associated mitochondrial dysfunction as a potential mechanism underlying ACLF. J Hepatol. 2020 Apr;72(4):688-701

2019

Aguilar D, Lemonnier N, Koppelman GH, Melén E, Oliva B, Pinart M, Guerra S, Bousquet J, Anto JM. Understanding allergic multimorbidity within the non-eosinophilic interactome. PLoS One. 2019 Nov 6;14(11):e0224448

Rodriguez RM, Suarez-Alvarez B, Lavín JL, Ascensión AM, Gonzalez M, Lozano JJ, Raneros AB, Bulnes PD, Vidal-Castiñeira JR, Huidobro C, Martin-Martin C, Sanz AB, Ruiz-Ortega M, Puig-Kröger A, Corbí AL, Araúzo-Bravo MJ, Aransay AM, Lopez-Larrea C. Signal Integration and Transcriptional Regulation of the Inflammatory Response Mediated by the GM-/M-CSF Signaling Axis in Human Monocytes. Cell Rep. 2019 Oct 22;29(4):860-872.e5

Marcuello M, Duran-Sanchon S, Moreno L, Lozano JJ, Bujanda L, Castells A, Gironella M. Analysis of A 6-Mirna Signature in Serum from Colorectal Cancer Screening Participants as Non-Invasive Biomarkers for Advanced Adenoma and Colorectal Cancer Detection. Cancers (Basel). 2019 Oct 12;11(10):1542

Maeso-Díaz R, Boyer-Diaz Z, Lozano JJ, Ortega-Ribera M, Peralta C, Bosch J, Gracia-Sancho J. New Rat Model of Advanced NASH Mimicking Pathophysiological Features and Transcriptomic Signature of The Human Disease. Cells. 2019 Sep 10;8(9):1062

Paul T, Blanco I, Aguilar D, Tura-Ceide O, Bonjoch C, Smolders VF et al. Therapeutic effects of soluble guanylate cyclase stimulation on pulmonary hemodynamics and emphysema development in guinea pigs chronically exposed to cigarette smoke. Am J Physiol Lung Cell Mol Physiol. 2019 Aug 1;317(2):L222-L234

Maeso-Díaz R, Ortega-Ribera M, Lafoz E, Lozano JJ, Baiges A, Francés R et al. Aging Influences Hepatic Microvascular Biology and Liver Fibrosis in Advanced Chronic Liver Disease. Aging Dis. 2019 Aug 1;10(4):684-698

Tubita V, Segui-Barber J, Lozano JJ, Banon-Maneus E, Rovira J, Cucchiari D et al. Effect of immunosuppression in miRNAs from extracellular vesicles of colorectal cancer and their influence on the pre-metastatic niche. Sci Rep. 2019 Aug 1;9(1):11177.

Prieto-Fernández E, Aransay AM, Royo F, González E, Lozano JJ, Santos-Zorrozua B et al. A Comprehensive Study of Vesicular and Non-Vesicular miRNAs from a Volume of Cerebrospinal Fluid Compatible with Clinical Practice. Theranostics. 2019 Jun 19;9(16):4567-4579

Argemi J, Latasa MU, Atkinson SR, Blokhin IO, Massey V, Gue JP et al. Defective HNF4alpha-dependent gene expression as a driver of hepatocellular failure in alcoholic hepatitis. Nat Commun. 2019 Jul 16;10(1):3126

Vila-Navarro E, Duran-Sanchon S, Vila-Casadesús M, Moreira L, Ginès À, Cuatrecasas M, Lozano JJ et al. Novel Circulating miRNA Signatures for Early Detection of Pancreatic Neoplasia. Clin Transl Gastroenterol. 2019 Apr;10(4):e00029

Díaz-Gay M, Franch-Expósito S, Arnau-Collell C, Park S, Supek F, Muñoz J et al. Integrated Analysis of Germline and Tumor DNA Identifies New Candidate Genes Involved in Familial Colorectal Cancer. Cancers (Basel). 2019 Mar 13;11(3)

Montalbo R, Lozano JJ, Izquierdo L, Ingelmo-Torres M, BaÑos C, Palou J et al. Transl Res. 2019 Jun;208:73-84

Reverter E, Lozano JJ, Alonso C, Berzigotti A, Seijo S, Turon F et al. Metabolomics discloses potential biomarkers to predict  the acute HVPG response to propranolol in patients with cirrhosis. Liver Int. 2019 Apr;39(4):705-713

Jassem W, Xystrakis E, Ghnewa YG, Yuksel M, Pop O, Martinez-Llordella M et al. Normothermic Machine Perfusion (NMP) Inhibits Proinflammatory Responses in the Liver and Promotes Regeneration. Hepatology. 2019 Aug;70(2):682-695

Torabi K, Erola P, Alvarez-Mora MI, Díaz-Gay M, Ferrer Q, Castells A et al. Quantitative analysis of somatically acquired and constitutive uniparental disomy in gastrointestinal cancers. Int J Cancer. 2019 Feb 1;144(3):513-524

2018

Izquierdo L, Mateu L, Lozano JJ, Montalbo R, Ingelmo-Torres M, Gómez A, Peri L, Mengual L, Franco A, Alcaraz A. Urine Gene Expression Profiles in Bladder Pain Syndrome Patients Treated with Triamcinolone. Eur Urol Focus. 2018 Oct 11

Han C, Mengual L, Kang B, Lozano JJ, Yang X, Zhang C, Alcaraz A, Liang J, YeD. Validation of Urine-based Gene Classifiers for Detecting Bladder Cancer in a Chinese Study. J Cancer. 2018 Aug 6;9(17):3208-3215

Feng S, Bucuvalas JC, Demetris AJ, Burrell BE, Spain KM, Kanaparthi S, MageeJC, Ikle D, Lesniak A, Lozano JJ, Alonso EM, Bray RA, Bridges NE, Doo E, GebelHM, Gupta NA, Himes RW, Jackson AM, Lobritto SJ, Mazariegos GV, Ng VL, Rand EB,Sherker AH, Sundaram S, Turmelle YP, Sanchez-Fueyo A. Evidence of ChronicAllograft Injury in Liver Biopsies From Long-term Pediatric Recipients of LiverTransplants. Gastroenterology. 2018 Aug 22. pii: S0016-5085(18)34888-z

Lario S, Brunet-Vega A, Quílez ME, Ramírez-Lázaro MJ, Lozano JJ,García-Martínez L, Pericay C, Miquel M, Junquera F, Campo R, Calvet X. Expressionprofile of circulating microRNAs in the Correa pathway of progression to gastric cancer. United European Gastroenterol J. 2018 Jun;6(5):691-701

Coll M, Perea L, Boon R, Leite SB, Vallverdú J, Mannaerts I, Smout A, ElTaghdouini A, Blaya D, Rodrigo-Torres D, Graupera I, Aguilar-Bravo B, Chesne C,Najimi M, Sokal E, Lozano JJ, van Grunsven LA, Verfaillie CM, Sancho-Bru P.Generation of Hepatic Stellate Cells from Human Pluripotent Stem Cells EnablesIn Vitro Modeling of Liver Fibrosis. Cell Stem Cell. 2018 Jul 5;23(1):101-113.e7.

Díaz-Gay M, Vila-Casadesús M, Franch-Expósito S, Hernández-Illán E, Lozano JJ,Castellví-Bel S. Mutational Signatures in Cancer (MuSiCa): a web application toimplement mutational signatures analysis in cancer samples. BMC Bioinformatics.2018 Jun 14;19(1):224

van der Heijden AG, Mengual L, Ingelmo-Torres M, Lozano JJ, van Rijt-van deWesterlo CCM, Baixauli M, Geavlete B, Moldoveanud C, Ene C, Dinney CP, CzerniakB, Schalken JA, Kiemeney LALM, Ribal MJ, Witjes JA, Alcaraz A. Urine cell-basedDNA methylation classifier for monitoring bladder cancer. Clin Epigenetics. 2018 May 30;10:71

Londoño MC, Souza LN, Lozano JJ, Miquel R, Abraldes JG, Llovet LP, Quaglia A, Rimola A, Navasa M, Sánchez-Fueyo A. Molecular profiling of subclinicalinflammatory lesions in long-term surviving adult liver transplant recipients. J Hepatol. 2018 Sep;69(3):626-634

Montalbo R, Izquierdo L, Ingelmo-Torres M, Lozano JJ, Capitán D, Alcaraz A,Mengual L. Prognostic value of circulating microRNAs in upper tract urinarycarcinoma. Oncotarget. 2018 Mar 30;9(24):16691-1670010.18632/oncotarget.24672. eCollection 2018 Mar 30

Vila-Casadesús M, Vila-Navarro E, Raimondi G, Fillat C, Castells A, Lozano JJ,Gironella M. Deciphering microRNA targets in pancreatic cancer using miRComb Rpackage. Oncotarget. 2018 Jan 8;9(5):6499-6517

Wangsa D, Quintanilla I, Torabi K, Vila-Casadesús M, Ercilla A, Klus G, Yuce Z, Galofré C, Cuatrecasas M, Lozano JJ, Agell N, Cimini D, Castells A, Ried T,Camps J. Near-tetraploid cancer cells show chromosome instability triggered byreplication stress and exhibit enhanced invasiveness. FASEB J. 2018Jul;32(7):3502-3517

Franch-Expósito S, Esteban-Jurado C, Garre P, Quintanilla I, Duran-Sanchon S,Díaz-Gay M, Bonjoch L, Cuatrecasas M, Samper E, Muñoz J, Ocaña T, Carballal S,López-Cerón M, Castells A; EPICOLON consortium, Vila-Casadesús M, Derdak S,Laurie S, Beltran S, Carvajal J, Bujanda L, Ruiz-Ponte C, Camps J, Gironella M,Lozano JJ, Balaguer F, Cubiella J, Caldés T, Castellví-Bel S. Rare germline copy number variants in colorectal cancer predisposition characterized by exomesequencing analysis. J Genet Genomics. 2018 Jan 20;45(1):41-45

Sánchez-Cid L, Pons M, Lozano JJ, Rubio N, Guerra-Rebollo M, Soriano A,Paris-Coderch L, Segura MF, Fueyo R, Arguimbau J, Zodda E, Bermudo R, Alonso I,Caparrós X, Cascante M, Rafii A, Kang Y, Martínez-Balbás M, Weiss SJ, Blanco J,Muñoz M, Fernández PL, Thomson TM. MicroRNA-200, associated with metastaticbreast cancer, promotes traits of mammary luminal progenitor cells. Oncotarget.2017 Sep 7;8(48):83384-83406

Planell N, Masamunt MC, Leal RF, Rodríguez L, Esteller M, Lozano JJ, Ramírez A, Ayrizono MLS, Coy CSR, Alfaro I, Ordás I, Visvanathan S, Ricart E, GuardiolaJ, Panés J, Salas A. Usefulness of Transcriptional Blood Biomarkers as aNon-invasive Surrogate Marker of Mucosal Healing and Endoscopic Response inUlcerative Colitis. J Crohns Colitis. 2017 Oct 27;11(11):1335-1346

Rius B, Duran-Güell M, Flores-Costa R, López-Vicario C, Lopategi A,Alcaraz-Quiles J, Casulleras M, Lozano JJ, Titos E, Clària J. The specializedproresolving lipid mediator maresin 1 protects hepatocytes from lipotoxic andhypoxia-induced endoplasmic reticulum stress. FASEB J. 2017 Dec;31(12):5384-5398.

Flórez-Grau G, Cabezón R, Borgman KJE, España C, Lozano JJ, Garcia-Parajo MF,Benítez-Ribas D. Up-regulation of EP(2) and EP(3) receptors in human tolerogenic dendritic cells boosts the immunosuppressive activity of PGE(2). J Leukoc Biol.2017 Sep;102(3):881-895

Whitehouse G, Gray E, Mastoridis S, Merritt E, Kodela E, Yang JHM, Danger R, Mairal M, Christakoudi S, Lozano JJ, Macdougall IC, Tree TIM, Sanchez-Fueyo A,Martinez-Llordella M. IL-2 therapy restores regulatory T-cell dysfunction inducedby calcineurin inhibitors. Proc Natl Acad Sci U S A. 2017 Jul3;114(27):7083-7088

Marín-Aguilera M, Reig Ò, Lozano JJ, Jiménez N, García-Recio S, Erill N, GabaL, Tagliapietra A, Ortega V, Carrera G, Colomer A, Gascón P, Mellado B.Correction: Molecular profiling of peripheral blood is associated withcirculating tumor cells content and poor survival in metastaticcastration-resistant prostate cancer. Oncotarget. 2017 Apr 18;8(16):2767310.18632/oncotarget.17148

Ingelmo-Torres M, Lozano JJ, Izquierdo L, Carrion A, Costa M, Gómez L, Ribal MJ, Alcaraz A, Mengual L. Urinary cell microRNA-based prognostic classifier fornon-muscle invasive bladder cancer. Oncotarget. 2017 Mar 14;8(11):18238-18247.doi: 10.18632/oncotarget.15315

Grañé-Boladeras N, Pérez-Torras S, Lozano JJ, Romero MR, Mazo A, Marín JJG,Pastor-Anglada M. Pharmacogenomic analyzis of the responsiveness ofgastrointestinal tumor cell lines to drug therapy: A transportome approach.Pharmacol Res. 2016 Nov;113(Pt A):364-375

Odena G, Chen J, Lozano JJ, Altamirano J, Rodrigo-Torres D, Affo S,Morales-Ibanez O, Matsushita H, Zou J, Dumitru R, Caballeria J, Gines P, ArroyoV, You M, Rautou PE, Valla D, Crews F, Seki E, Sancho-Bru P, Bataller R. LPS-TLR4Pathway Mediates Ductular Cell Expansion in Alcoholic Hepatitis. Sci Rep. 2016Oct 18;6:35610

Titos E, Rius B, López-Vicario C, Alcaraz-Quiles J, García-Alonso V, LopategiA, Dalli J, Lozano JJ, Arroyo V, Delgado S, Serhan CN, Clària J. Signaling andImmunoresolving Actions of Resolvin D1 in Inflamed Human Visceral Adipose Tissue.J Immunol. 2016 Oct 15;197(8):3360-3370. Epub 2016 Sep 19

Meireles CZ, Pasarin M, Lozano JJ, García-Calderó H, Gracia-Sancho J,García-Pagán JC, Bosch J, Abraldes JG. Simvastatin Attenuates Liver Injury inRodents with Biliary Cirrhosis Submitted to Hemorrhage/Resuscitation. Shock. 2017Mar;47(3):370-377

Planque C, Rajabi F, Grillet F, Finetti P, Bertucci F, Gironella M, LozanoJJ, Beucher B, Giraud J, Garambois V, Vincent C, Brown D, Caillo L, Kantar J,Pelegrin A, Prudhomme M, Ripoche J, Bourgaux JF, Ginestier C, Castells A,Hollande F, Pannequin J, Pascussi JM. Pregnane X-receptor promotes stemcell-mediated colon cancer relapse. Oncotarget. 2016 Aug 30;7(35):56558-56573.doi: 10.18632/oncotarget.10646

van der Heijden AG, Mengual L, Lozano JJ, Ingelmo-Torres M, Ribal MJ,Fernández PL, Oosterwijk E, Schalken JA, Alcaraz A, Witjes JA. A five-geneexpression signature to predict progression in T1G3 bladder cancer. Eur J Cancer.2016 Sep;64:127-36

Vila-Navarro E, Vila-Casadesús M, Moreira L, Duran-Sanchon S, Sinha R, Ginés À, Fernández-Esparrach G, Miquel R, Cuatrecasas M, Castells A, Lozano JJ,Gironella M. MicroRNAs for Detection of Pancreatic Neoplasia: Biomarker Discoveryby Next-generation Sequencing and Validation in 2 Independent Cohorts. Ann Surg. 2017 Jun;265(6):1226-1234

Tovar V, Cornella H, Moeini A, Vidal S, Hoshida Y, Sia D, Peix J, Cabellos L,Alsinet C, Torrecilla S, Martinez-Quetglas I, Lozano JJ, Desbois-Mouthon C, Solé M, Domingo-Domenech J, Villanueva A, Llovet JM. Tumour initiating cells andIGF/FGF signalling contribute to sorafenib resistance in hepatocellularcarcinoma. Gut. 2017 Mar;66(3):530-540

Blaya D, Coll M, Rodrigo-Torres D, Vila-Casadesús M, Altamirano J, Llopis M, Graupera I, Perea L, Aguilar-Bravo B, Díaz A, Banales JM, Clària J, Lozano JJ,Bataller R, Caballería J, Ginès P, Sancho-Bru P. Integrative microRNA profilingin alcoholic hepatitis reveals a role for microRNA-182 in liver injury andinflammation. Gut. 2016 Sep;65(9):1535-45

Esteban-Jurado C, Franch-Expósito S, Muñoz J, Ocaña T, Carballal S,López-Cerón M, Cuatrecasas M, Vila-Casadesús M, Lozano JJ, Serra E, Beltran S,Brea-Fernández A, Ruiz-Ponte C, Castells A, Bujanda L, Garre P, Caldés T,Cubiella J, Balaguer F, Castellví-Bel S. The Fanconi anemia DNA damage repairpathway in the spotlight for germline predisposition to colorectal cancer. Eur J Hum Genet. 2016 Oct;24(10):1501-5

Abulí A, Castells A, Bujanda L, Lozano JJ, Bessa X, Hernández C,Álvarez-Urturi C, Pellisé M, Esteban-Jurado C, Hijona E, Burón A, Macià F, GrauJ, Guayta R, Castellví-Bel S, Andreu M; PROCOLON research group. Genetic VariantsAssociated with Colorectal Adenoma Susceptibility. PLoS One. 2016 Apr14;11(4):e0153084

Vila-Casadesús M, Gironella M, Lozano JJ. MiRComb: An R Package to AnalysemiRNA-mRNA Interactions. Examples across Five Digestive Cancers. PLoS One. 2016Mar 11;11(3):e0151127

Pérez-Torras S, Iglesias I, Llopis M, Lozano JJ, Antolín M, Guarner F,Pastor-Anglada M. Transportome Profiling Identifies Profound Alterations inCrohn's Disease Partially Restored by Commensal Bacteria. J Crohns Colitis. 2016 Jul;10(7):850-9

Mengual L, Lozano JJ, Ingelmo-Torres M, Izquierdo L, Musquera M, Ribal MJ,Alcaraz A. Using gene expression from urine sediment to diagnose prostate cancer:development of a new multiplex mRNA urine test and validation of currentbiomarkers. BMC Cancer. 2016 Feb 9;16:76

Ribal MJ, Mengual L, Lozano JJ, Ingelmo-Torres M, Palou J, Rodríguez-Faba O, Witjes JA, Van der Heijden AG, Medina R, Conde JM, Marberger M, Schmidbauer J,Fernández PL, Alcaraz A. Gene expression test for the non-invasive diagnosis of bladder cancer: A prospective, blinded, international and multicenter validation study. Eur J Cancer. 2016 Feb;54:131-138

Bonaccorsi-Riani E, Pennycuick A, Londoño MC, Lozano JJ, Benítez C, Sawitzki B, Martínez-Picola M, Bohne F, Martínez-Llordella M, Miquel R, Rimola A,Sánchez-Fueyo A. Molecular Characterization of Acute Cellular Rejection OccurringDuring Intentional Immunosuppression Withdrawal in Liver Transplantation. Am JTransplant. 2016 Feb;16(2):484-96

Seijo S, Lozano JJ, Alonso C, Miquel R, Berzigotti A, Reverter E, Turon F, Martinez-Chantar ML, Castro A, Mato JM, Hernández-Gea V, Bosch J,Garcí-Pagan JC. Metabolomics as a diagnostic tool for idiopathic non-cirrhotic portal hypertension. Liver Int. 2015 Sep 23.

Bonaccorsi-Riani E, Danger R, Lozano JJ, Martinez-Picola M, Kodela E,Mas-Malavila R, Bruguera M, Collins HL, Hider RC, Martinez-Llordella M,Sanchez-Fueyo A. Iron Deficiency Impairs Intra-Hepatic Lymphocyte Mediated Immune Response. PLoS One. 2015 Aug 19;10(8):e0136106. doi: 10.1371/journal.pone.0136106.eCollection 2015

Blasi A, Beltran J, Martin N, Martinez-Palli G, Lozano JJ, Balust J,Torrents A, Taura P. Transient hyperglycemia during liver transplantation does not affect the early graft function. Ann Hepatol. 2015 Sep-Oct;14(5):675-87

Torabi K, Miro R, Fernandez-Jimenez N, Quintanilla I, Ramos L, Prat E, Del Rey J, Pujol N, Killian JK, Meltzer PS, Fernandez PL, Ried T, Lozano JJ, Camps J, Ponsa I. Patterns of somatic uniparental disomy identify novel tumor suppressor genes in colorectal cancer. Carcinogenesis. 2015 Oct;36(10):1103-10. doi: 10.1093/carcin/bgv115. Epub 2015 Aug 4

Dumontet E, Danger R, Vagefi PA, Londono MC, Pallier A, Lozano JJ, Giral M, Degauque N, Soulillou JP, Martinez-Llordella M, Lee H, Latournerie M, Boudjema K, Dulong J, Tarte K, Sanchez-Fueyo A, Feng S, Brouard S, Conchon S. Peripheral phenotype and gene expression profiles of combined liver-kidney transplant patients. Liver Int. 2015 Jul 20.

Coll M, El Taghdouini A, Perea L, Mannaerts I, Vila-Casadesus M, Blaya D, Rodrigo-Torres D,Affo S, Morales-Ibanez O, Graupera I, Lozano JJ, Najimi M, Sokal E, Lambrecht J, Ginès P, van Grunsven LA, Sancho-Bru P. Integrative miRNA and Gene Expression Profiling Analysis of Human Quiescent Hepatic Stellate Cells. Sci Rep. 2015 Jun 22;5:11549.

Marin-Aguilera M, Reig O, Lozano JJ, Jimenez N, Garcia-Recio S, Erill N, Gaba L, Tagliapietra A, Ortega V, Carrera G, Colomer A, Gascon P, Mellado B. Molecular profiling of peripheral blood is associated with circulating tumor cells content and poor survival in metastatic castration-resistant prostate cancer. Oncotarget. 2015 Apr 30;6(12):10604-16

Cabezon R, Carrera-Silva EA, Florez-Grau G, Errasti AE, Calderon-Gomez E, Lozano JJ, Espana C, Ricart E, Panes J, Rothlin CV, Benitez-Ribas D. MERTK as negative regulator of human T cell activation. J Leukoc Biol. 2015 Apr;97(4):751-60.

Farres J, Llacuna L, Martin-Caballero J, Martinez C, Lozano JJ, Ampurdanes C,Lopez-Contreras AJ, Florensa L, Navarro J, Ottina E, Dantzer F, Schreiber V, Villunger A, Fernández-Capetillo O, Yelamos J. PARP-2 sustains erythropoiesis in mice by limiting replicative stress in erythroid progenitors. Cell Death Differ. 2015 Jul;22(7):1144-57. doi: 10.1038/cdd.2014.202. Epub 2014 Dec 12

Esteban-Jurado C, Vila-Casadesus M, Garre P, Lozano JJ, Pristoupilova A, Beltran S, Munoz J, Ocana T, Balaguer F, Lopez-Ceron M, Cuatrecasas M, Franch-Exposito S, Pique JM, Castells A, Carracedo A, Ruiz-Ponte C, Abuli A, Bessa X, Andreu M, Bujanda L, Caldes T, Castellvi-Bel S. Whole-exome sequencing identifies rare pathogenic variants in new predisposition genes for familial colorectal cancer. Genet Med. 2014 Jul 24. doi: 10.1038/gim.2014.89

Bohne F, Londono MC, Benitez C, Miquel R, Martinez-Llordella M, Russo C, Ortiz C, Bonaccorsi-Riani E, Brander C, Bauer T, Protzer U, Jaeckel E, Taubert R, Forns X, Navasa M, Berenguer M, Rimola A, Lozano JJ, Sanchez-Fueyo A. HCV-Induced Immune Responses Influence the Development of Operational Tolerance After Liver Transplantation in Humans. Sci Transl Med. 2014 Jun 25;6(242):242ra81. doi:10.1126/scitranslmed.3008793

Alonso-Espinaco V, Cuatrecasas M, Alonso V, Escudero P, Marmol M, Horndler C, Ortego J, Gallego R, Codony-Servat J, Garcia-Albeniz X, Jares P, Castells A, Lozano JJ, Rosell R, Maurel J. RAC1b overexpression correlates with poor prognosis in KRAS/BRAF WT metastatic colorectal cancer patients treated with first-line FOLFOX/XELOX chemotherapy. Eur J Cancer. 2014 Jul;50(11):1973-81. doi: 10.1016/j.ejca.2014.04.019. Epub 2014 May 12

Leal RF, Planell N, Kajekar R, Lozano JJ, Ordas I, Dotti I, Esteller M, Masamunt MC, Parmar H, Ricart E, Panes J, Salas A. Identification of inflammatory mediators in patients with Crohn's disease unresponsive to anti-TNFa therapy. Gut. 2014 Apr 3. doi: 10.1136/gutjnl-2013-306518

Rodrigo-Torres D, Affo S, Coll M, Morales-Ibanez O, Millan C, Blaya D, Alvarez-Guaita A, Rentero C, Lozano JJ, Maestro MA, Solar M, Arroyo V, Caballerí J, van Grunsven LA, Enrich C, Gines P, Bataller R, Sancho-Bru P. The biliary epithelium gives rise to liver progenitor cells. Hepatology. 2014 Feb 20.

Gonzalo V, Lozano JJ, Alonso-Espinaco V, Moreira L, Munoz J, Pellise M, Castellvi-Bel S, Bessa X, Andreu M, Xicola RM, Llor X, Ruiz-Ponte C, Carracedo A, Jover R, Castells A, Balaguer F Multiple Sporadic Colorectal Cancers Display a Unique Methylation Phenotype. PLoS One. 2014 Mar 18;9(3):e91033

Varela-Rey M, Iruarrizaga-Lejarreta M, Lozano JJ, Aransay AM, Fernandez AF, Lavin JL, Mosen-Ansorena D, Berdasco M, Turmaine M, Luka Z, Wagner C, Lu SC, Esteller M, Mirsky R, Jessen KR, Fraga MF, Martinez-Chantar ML, Mato JM, Woodhoo A.S-adenosylmethionine Levels Regulate the Schwann Cell DNA Methylome. Neuron. 2014 Mar 5;81(5):1024-39

Esteban-Jurado C, Garre P, Vila M, Lozano JJ, Pristoupilova A, Beltran S, Abuli A, Munoz J, Balaguer F, Ocana T, Castells A, Pique JM, Carracedo A, Ruiz-Ponte C, Bessa X, Andreu M, Bujanda L, Caldes T, Castellvi-Bel S. New genes emerging for colorectal cancer predisposition. World J Gastroenterol. 2014 Feb 28;20(8):1961-1971. Review

Marin-Aguilera M, Codony-Servat J, Reig O, Lozano JJ, Fernandez PL, Pereira MV, Jimenez N, Donovan M, Puig P, Mengual L, Bermudo R, Font A, Gallardo E,Ribal MJ, Alcaraz A, Gascon P, Mellado B. Epithelial-to-mesenchymal transition mediates docetaxel resistance and high risk of relapse in prostate cancer. Mol Cancer Ther. 2014 Mar 21

Botta-Orfila T, Morato X, Compta Y, Lozano JJ, Falgas N, Valldeoriola F, Pont-Sunyer C, Vilas D, Mengual L, Fernandez M, Molinuevo JL, Antonell A, Marti MJ, Fernandez-Santiago R, Ezquerra M. Identification of blood serum micro-RNAs associated with idiopathic and LRRK2 Parkinson's disease. J Neurosci Res. 2014 Mar 20. doi: 10.1002/jnr.23377

Berardis S, Lombard C, Evraerts J, El Taghdouini A, Rosseels V, Sancho-Bru P, Lozano JJ, van Grunsven L, Sokal E, Najimi M. Gene expression profiling and secretome analysis differentiate adult-derived human liver stem/progenitor cells and human hepatic stellate cells. PLoS One. 2014 Jan 21;9(1):e86137

Mengual L, Ars E, Lozano JJ, Burset M, Izquierdo L, Ingelmo-Torres M, Gaya JM, Algaba F, Villavicencio H, Ribal MJ, Alcaraz A. Gene expression profiles in prostate cancer: Identification of candidate non-invasive diagnostic markers. Actas Urol Esp. 2013 Oct 24

Calvo J, Sanchez-Cid L, Munoz M, Lozano JJ, Thomson TM, Fernandez PL. Infrequent loss of luminal differentiation in ductal breast cancer metastasis. PLoS One. 2013 Oct 21;8(10):e78097

Izquierdo L, Ingelmo-Torres M, Mallofre C,Lozano JJ, Verhasselt-Crinquette M, Leroy X, Colin P, Comperat E, Roupret M, Alcaraz A, Mengual L. Prognostic Value Of Microrna Expression Pattern In Upper Tract Urothelial Carcinoma. BJU Int. 2013 Nov 1

Mengual L, Ribal MJ, Lozano JJ, Ingelmo-Torres M, Burset M, Fernandez PL,Alcaraz A. Validation study of a noninvasive urine test for diagnosis and prognosis assessment of bladder cancer: evidence for improved models. J Urol. 2014 Jan;191(1):261-9

Tingaud-Sequeira A, Lozano JJ, Zapater C, Otero D, Kube M, Reinhardt R,Cerda J. A rapid transcriptome response is associated with desiccation resistance in aerially-exposed killifish embryos. PLoS One. 2013 May 31;8(5):e64410. doi: 10.1371/journal.pone.0064410

Abuli A, Lozano JJ, Rodriguez-Soler M, Jover R, Bessa X, Munoz J,Esteban-Jurado C, Fernandez-Rozadilla C, Carracedo A, Ruiz-Ponte C, Cubiella J, Balaguer F, Bujanda L, Rene JM, Clofent J, Morillas JD, Nicolas-Perez D,Xicola RM, Llor X,Pique JM, Andreu M, Castells A, Castellví-Bel S; for the Gastrointestinal Oncology Group of the Spanish Gastroenterological Association. Genetic Susceptibility variants associated with colorrectal cancer prognosis. Carcinogenesis. 2013 May 27

Mengual L, Lozano JJ, Ingelmo-Torres M, Gazquez C, Ribal MJ, Alcaraz A. Using microRNA profiling in urine samples to develop a non-invasive test for bladder cancer. Int J Cancer. 2013 May 17.

Farres J, Martin-Caballero J, Martinez C, Lozano JJ, Llacuna L, Ampurdanes C, Ruiz-Herguido C, Dantzer F, Schreiber V, Villunger A, Bigas A,Yelamos J. PARP-2 is required to maintain hematopoiesis following sublethal γ-irradiation in mice. Blood. 2013 May 15

Benitez C, Londono MC, Miquel R, Manzia TM, Abraldes JG, Lozano JJ, Martínez-Llordella M, López M, Angelico R, Bohne F, Sese P, Daoud F, Larcier P, Roelen DL, Claas F, Whitehouse G, Lerut J, Pirenne J, Rimola A, Tisone G, Sánchez-Fueyo A. Prospective multi-center clinical trial of immunosuppressive drug withdrawal in stable adult liver transplant recipients. Hepatology. 2013 Mar 26. doi: 10.1002/hep.26426

Lopez-Vicario C, Gonzalez-Periz A, Rius B, Moran-Salvador E, Garcia-Alonso V, Lozano JJ, Bataller R, Cofan M, Kang JX, Arroyo V, Claria J, Titos E. Molecular interplay between Δ5/Δ6 desaturases and long-chain fatty acids in the pathogenesis of non-alcoholic steatohepatitis. Gut. 2013 Mar 14

Link A, Balaguer F, Shen Y, Lozano JJ, Leung HC, Boland CR, Goel A. Curcumin modulates DNA methylation in colorectal cancer cells. PLoS One. 2013;8(2):e57709

Seijo S, Lozano JJ, Alonso C, Reverter E, Miquel R, Abraldes JG, Martinez-Chantar ML, Garcia-Criado A, Berzigotti A, Castro A, Mato JM, Bosch J, Garcia-Pagan JC. Metabolomics Discloses Potential Biomarkers for the Noninvasive Diagnosis of Idiopathic Portal Hypertension. Am J Gastroenterol. 2013 Feb 19

Giraldez MD, Lozano JJ, Ramírez G, Hijona E, Bujanda L, Castells A,Gironella M. Circulating MicroRNAs as Biomarkers of Colorectal Cancer: Results from a Genome-Wide Profiling and Validation Study. Clin Gastroenterol Hepatol. 2012 Dec 22

Jin S, Chin J, Seeber S, Niewoehner J, Weiser B, Beaucamp N, Woods J, Murphy C, Fanning A, Shanahan F, Nally K, Kajekar R, Salas A, Planell N, Lozano J,Panes J, Parmar H, Demartino J, Narula S, Thomas-Karyat DA. TL1A/TNFSF15 directly induces proinflammatory cytokines, including TNFα, from CD3+CD161+ T cells to exacerbate gut inflammation. Mucosal Immunol. 2012 Dec 19

Planell N, Lozano JJ, Mora-Buch R, Masamunt MC, Jimeno M, Ordas I, Esteller M, Ricart E, Pique JM, Panes J, Salas A. Transcriptional analysis of the intestinal mucosa of patients with ulcerative colitis in remission reveals lasting epithelial cell alterations. Gut. 2012 Nov 7

Revilla-Nuin B, Parrilla P, Lozano J, Martinez de Haro LF, Ortiz A, Martínez C, Munitiz V, Ruiz de Angulo D, Bermejo J, Molina J, Cayuela ML, Yelamos J. Predictive Value of MicroRNAs in the Progression of Barrett Esophagus to Adenocarcinoma in a Long-Term Follow-Up Study. Ann Surg. 2012 Oct 10

Vazquez-Chantada M, Gonzalez-Lahera A, Martinez-Arranz I, Garcia-Monzon C, Regueiro MM, Garcia-Rodriguez JL, Schlangen KA, Mendibil I, Rodriguez-Ezpeleta N, Lozano JJ, Banasik K, Justesen JM, Joergensen T, Witte DR, Lauritzen T, Hansen T, Pedersen O, Veyrie N, Clement K, Tordjman J, Tran A, Marchand-Brustel YL, Buque X, Aspichueta P, Echevarria-Uraga JJ, Martin-Duce A, Caballeria J, Gual P, Castro A, Mato JM, Martinez-Chantar ML, Aransay AM. Solute carrier family 2 member 1 (SLC2A1) is involved in the development of nonalcoholic fatty liver disease. Hepatology. 2012 Sep 7.PMID:22961556

Giraldez MD, Lozano JJ, Cuatrecasas M, Alonso-Espinaco V, Maurel J,Marmol M, Horndler C, Ortego J, Alonso V, Escudero P, Ramirez G, Petry C, Lasalvia L, Bohmann K, Wirtz R, Mira A, Castells A. Gene-expression signature of tumor recurrence in patients with stage II and III colon cancer treated with 5'fluoruracil-based adjuvant chemotherapy. Int J Cancer. 2012 Jul 26

Martinez-Lopez N, Garcia-Rodriguez JL, Varela-Rey M, Gutierrez V, Fernandez-Ramos D, Beraza N, Aransay AM, Schlangen K, Lozano JJ, Aspichueta P, Luka Z, Wagner C, Evert M, Calvisi DF, Lu SC, Mato JM, Martinez-Chantar ML. Hepatoma Cells from Mice Deficient in Glycine N-Methyltransferase Have Increased RAS Signaling and Activation of Liver Kinase B1. Gastroenterology. 2012 Jun 8

Affo S, Dominguez M, Lozano JJ, Sancho-Bru P, Rodrigo-Torres D, Morales-Ibanez O, Moreno M, Millan C, Loaeza-Del-Castillo A, Altamirano J, Garcia-Pagan JC, Arroyo V, Gines P, Caballeria J, Schwabe RF, Bataller R. Transcriptome analysis identifies TNF superfamily receptors as potential therapeutic targets in alcoholic hepatitis. Gut. 2012 May 25

Roman J, Planell N, Lozano JJ, Aceituno M, Esteller M, Pontes C, Balsa D, Merlos M, Panes J, Salas A. Evaluation of responsive gene expression as a sensitive and specific biomarker in patients with ulcerative colitis.Inflamm Bowel Dis. 2012 May 17. pdf

Lario S, Ramirez-Lazaro MJ, Aransay AM, Lozano JJ, Montserrat A, Casalots A, Junquera F, Alvarez J, Segura F, Campo R, Calvet X. microRNA profiling in duodenal ulcer disease caused by Helicobacter pylori infection in a Western population. Clin Microbiol Infect. 2012 Mar 24. pdf, mat supl

Celia-Terrassa T, Meca-Cortes O, Mateo F, Martinez de Paz A, Rubio N, Arnal-Estape A, Ell BJ, Bermudo R, Diaz A, Guerra-Rebollo M, Lozano JJ, Estaras C, Ulloa C, Rholvarez-Simon D, Mila J, Vilella R, Paciucci R, Martínez-Balbas M, Garcia de Herreros A, Gomis RR, Kang Y, Blanco J, Fernandez PL, Thomson TM. Epithelial-mesenchymal transition can suppress major attributes of human epithelial tumor-initiating cells. J Clin Invest. 2012 Apr 16. pii: 59218. doi: 10.1172/JCI59218

Iruarrizaga-Lejarreta M, Varela-Rey M, Lozano JJ, Fernandez-Ramos D, Rodriguez-Ezpeleta N, Embade N, Lu SC, van der Kraan PM, Blaney Davidson EN, Gorospe M, Mirsky R, Jessen KR, Aransay AM, Mato JM, Martinez-Chantar ML, Woodhoo A. The RNA-Binding Protein Human Antigen R Controls Global Changes in Gene Expression during Schwann Cell Development. J Neurosci. 2012 Apr 4;32(14):4944-4958

Mercader JM, Gonzalez JR, Lozano JJ, Bak M, Kauppinen S, Sumoy L, Dierssen M, Fernandez-Aranda F, Visa J, Gratacos M, Estivill X. Aberrant brain microRNA target and miRISC gene expression in the anx/anx anorexia mouse model.Gene. 2012 Jan 30

Danger R, Pallier A, Giral M, Martinez-Llordella M, Lozano JJ, Degauque N, Sanchez-Fueyo A, Soulillou JP, Brouard S. Upregulation of miR-142-3p in Peripheral Blood Mononuclear Cells of Operationally Tolerant Patients with a Renal Transplant. J Am Soc Nephrol. 2012 Jan 26

Sancho-Bru P, Altamirano J, Rodrigo-Torres D, Coll M, Millan C, Lozano JJ, Miquel R, Arroyo V, Caballeria J, Gines P, Bataller R. Liver progenitor cell markers correlate with liver damage and predict short-term mortality in patients with alcoholic hepatitis. Hepatology. 2012 Jan 25. doi: 10.1002/hep.25614

Bohne F, Martinez-Llordella M, Lozano JJ, Miquel R, Benitez C, Londono MC, Manzia TM, Angelico R, Swinkels DW, Tjalsma H, Lopez M, Abraldes JG, Bonaccorsi-Riani E, Jaeckel E, Taubert R, Pirenne J, Rimola A, Tisone G, Sanchez-Fueyo A. Intra-graft expression of genes involved in iron homeostasis predicts the development of operational tolerance in human liver transplantation. J Clin Invest. 2011 Dec 12

Balaguer F, Moreira L, Lozano JJ, Link A, Ramirez G, Shen Y, Cuatrecasas M, Arnold M, Meltzer SJ, Syngal S, Stoffel E, Jover Martinez R, Llor X, Castells A, Boland CR, Gironella M, Goel A. Colorectal cancers with microsatellite instability display unique miRNA profiles. Clin Cancer Res. 2011 Aug 15.

Lozano JJ, Pallier A, Martinez-Llordella M, Danger R, López M, Giral M,Londono MC, Rimola A, Soulillou JP, Brouard S, Sánchez-Fueyo A. Comparison of Transcriptional and Blood Cell-Phenotypic Markers Between Operationally Tolerant Liver and Kidney Recipients. Am J Transplant. 2011 Aug 9

Llorens F, Hummel M, Pastor X, Ferrer A, Pluvinet R, Vivancos A, Castillo E,Iraola S, Mosquera AM, Gonzalez E, Lozano J, Ingham M, Dohm JC, Noguera M, Kofler R, Del Rio JA, Bayes M, Himmelbauer H, Sumoy L. Multiple platform assessment of the EGF dependent transcriptome by microarray and deep tag sequencing analysis. BMC Genomics. 2011 Jun 23;12(1):326
Brouard S, Puig-Pey I, Lozano JJ, Pallier A, Braud C, Giral M, Guillet M,Londono MC, Oppenheimer F, Campistol JM, Soulillou JP, Sanchez-Fueyo A. Comparative Transcriptional and Phenotypic Peripheral Blood Analysis of Kidney Recipients Under Cyclosporin A or Sirolimus Monotherapy. Am J Transplant. 2010 Dec;10(12):2604-2614

Ko KS, Tomasi ML, Iglesias-Ara A, French BA, French SW, Ramani K, Lozano JJ, Oh P, He L, Stiles BL, Li TW, Yang H, Martínez-Chantar ML, Mato JM, Lu SC. Liver-specific deletion of prohibitin 1 results in spontaneous liver injury, fibrosis, and hepatocellular carcinoma in mice. Hepatology. 2010 Aug 20

Benítez CE, Puig-Pey I, López M, Martínez-Llordella M,Lozano JJ, Bohne F, Londono MC, García-Valdecasas JC, Bruguera M, Navasa M, Rimola A,Sánchez-Fueyo A. ATG-Fresenius Treatment and Low-Dose Tacrolimus: Results of a Randomized Controlled Trial in Liver Transplantation. Am J Transplant. 2010 Oct;10(10):2296-304

Balaguer F, A, Lozano JJ, Cuatrecasas M, Nagasaka T, Boland CR, Goel A. Epigenetic Silencing of miR-137 Is an Early Event in Colorectal Carcinogenesis. Cancer Res. 2010 Aug 3

Link A, Balaguer F, Shen Y, Nagasaka T, Lozano JJ, Boland CR, Goel A. Fecal MicroRNAs as Novel Biomarkers for Colon Cancer Screening. Cancer Epidemiol Biomarkers Prev. 2010 Jun 15

Pallier A, Hillion S, Danger R, Giral M, Racapé M, Degauque N, Dugast E,Ashton-Chess J, Pettré S,Lozano JJ, Bataille R, Devys A, Cesbron-Gautier A, Braudeau C, Larrose C, Soulillou JP, Brouard S. Patients with drug-free long-term graft function display increased numbers of peripheral B cells with a memory and inhibitory phenotype. Kidney Int. 2010 Jun 9

Puig-Pey I, Bohne F, Benítez C, López M, Martínez-Llordella M, Oppenheimer F,Lozano JJ, González-Abraldes J, Tisone G, Rimola A, Sánchez-Fueyo A. Characterization of gammadelta T cell subsets in organ transplantation. Transpl Int. 2010 May 5

Titos E, Ferré N, Lozano JJ, Horrillo R, López-Parra M, Arroyo V, Clària J. Protection From Hepatic Lipid Accumulation And Inflammation By Genetic Ablation Of 5-Lipoxygenase. Prostaglandins Other Lipid Mediat. 2010 Mar 11. PMID: 20227514

Moreno M, Chaves JF, Sancho-Bru P, Ramalho F, Ramalho LN, Mansego ML, Ivorra C, Dominguez M, Conde L, Millán C, Marí M, Colmenero J, Lozano JJ, Jares P, Vidal J, Forns X, Arroyo V, Caballería J, Ginès P, Bataller R. Ghrelin attenuates hepatocellular injury and liver fibrogenesis in rodents and influences fibrosis progression in humans
Hepatology. 2010 Mar;51(3):974-85

Armengol G, Knuutila S, Lozano JJ, Madrigal I, Caballín MR. Identification of human specific gene duplications relative to other primates by array CGH and quantitative PCR. Genomics. 2010 Feb 11. PMID: 20153417

Tingaud-Sequeira A, Calusinska M, Finn RN, Chauvigné F, Lozano J, Cerdà J. The zebrafish genome encodes the largest vertebrate repertoire of functional aquaporins with dual paralogy and substrate specificities similar to mammals. BMC Evol Biol. 2010 Feb 11;10:38

Gonzalo V, Lozano JJ, Munoz J, Balaguer F, Pellisé M, Rodríguez de Miguel C, Andreu M, Jover R, Llor X, Giráldez MD, Ocaña T, Serradesanferm A, Alonso-Espinaco V, Jimeno M, Cuatrecasas M, Sendino O, Castellví-Bel S, Castells A; Gastrointestinal Oncology Group of the Spanish Gastroenterological Association. Aberrant gene promoter methylation associated with sporadic multiple colorectal cancer. PLoS One. 2010 Jan 19;5(1):e8777

Soler M, Mancini F, Meca-Cortés O, Sánchez-Cid L, Rubio N, López-Fernández S, Lozano JJ, Blanco J, Fernández PL, Thomson TM. HER3 is required for the maintenance of neuregulin-dependent and -independent attributes of malignant progression in prostate cancer cells. Int J Cancer. 2009 Dec 1;125(11):2565-75

Tingaud-Sequeira A, Chauvigné F, Lozano J, Agulleiro MJ, Asensio E, Cerdà J. New insights into molecular pathways associated with flatfish ovarian development and atresia revealed by transcriptional analysis. BMC Genomics. 2009 Sep 15;10:434

Mengual L, Burset M, Ars E, Lozano JJ, Villavicencio H, Ribal MJ, Alcaraz A. DNA microarray expression profiling of bladder cancer allows identification of noninvasive diagnostic markers. J Urol. 2009 Aug;182(2):741-8. Epub 2009 Jun 18.PMID: 19539325

Benítez C, Lozano JJ, Fueyo AS. Gene expression profiling and transplantation tolerance in the clinic. Transplantation. 2009 Aug 15;88(3 Suppl):S50-3. Review.PMID: 19667962

Servitja JM, Pignatelli M, Maestro MA, Cardalda C, Boj SF,Lozano J, Blanco E, Lafuente A, McCarthy MI ,Sumoy L, Guigó R, Ferrer J. Hnf1~ (MODY3) controls tissue-specific transcriptional programs and exerts opposed effects on cell growth in pancreatic islets and liver. Molecular Cell Biology 2009 Jun;29(11):2945-59

Muñoz MJ, Pérez Santangelo MS, Paronetto MP, de la Mata M, Pelisch F, Boireau S, Glover-Cutter K, Ben-Dov C, Blaustein M, Lozano JJ, Bird G, Bentley D, Bertrand E, Kornblihtt AR. DNA damage regulates alternative splicing through inhibition of RNA polymerase II elongation. Cell. 2009 May 15;137(4):708-20. Erratum in: Cell. 2009 Oct 2;139(1):211